Mike

Is Spironolactone same as Triamterene?

UK Pharmacist

Similar, in that they are both used as diuretics, but they are from
different classes and work by different physiological mechanisms.


NPS



On Sat, 13 Jan 2007 23:52:05 GMT, "Mike" <mike@hotmail.com> wrote:

>Is Spironolactone same as Triamterene?

Mike

Do you mean Triamterene does not block aldosterone, but works differently?

"UK Pharmacist" <ukpharmacist@uk_pharmacy.com> wrote in message
news:hoepq210pvnmlmdts2gr42vi7ac7u2frn3@4ax.com...
> Similar, in that they are both used as diuretics, but they are from
> different classes and work by different physiological mechanisms.
>
>
> NPS
>
>
>
> On Sat, 13 Jan 2007 23:52:05 GMT, "Mike" <mike@hotmail.com> wrote:
>
>>Is Spironolactone same as Triamterene?

UK Pharmacist

Yes.

"Triamterene has a unique mode of action; it inhibits the reabsorption
of sodium ions in exchange for potassium and hydrogen ions at that
segment of the distal tubule under the control of adrenal
mineralocorticoids (especially aldosterone). This activity is not
directly related to aldosterone secretion or antagonism; it is a
result of a direct effect on the renal tubule." (from:
www.rxlist.com/cgi/generic/triamterine_cp.htm - Clinical Pharmacology
tab).

The same site can give information on Spironolactone for comparison
(www.rxlist.com/cgi/generic/spiron_cp.htm).




On Thu, 18 Jan 2007 00:29:58 GMT, "Mike" <mike@hotmail.com> wrote:

>Do you mean Triamterene does not block aldosterone, but works differently?
>

Mike

Thanks a lot UK Pharmacist.

"UK Pharmacist" <ukpharmacist@uk_pharmacy.com> wrote in message
news:qqsvq2tfj3632iqdqu0dcdbnk2v6j4ff1u@4ax.com...
> Yes.
>
> "Triamterene has a unique mode of action; it inhibits the reabsorption
> of sodium ions in exchange for potassium and hydrogen ions at that
> segment of the distal tubule under the control of adrenal
> mineralocorticoids (especially aldosterone). This activity is not
> directly related to aldosterone secretion or antagonism; it is a
> result of a direct effect on the renal tubule." (from:
> www.rxlist.com/cgi/generic/triamterine_cp.htm - Clinical Pharmacology
> tab).
>
> The same site can give information on Spironolactone for comparison
> (www.rxlist.com/cgi/generic/spiron_cp.htm).
>
>
>
>
> On Thu, 18 Jan 2007 00:29:58 GMT, "Mike" <mike@hotmail.com> wrote:
>
>>Do you mean Triamterene does not block aldosterone, but works differently?
>>

PH

UK Pharmacist wrote:
> Yes.
>
> "Triamterene has a unique mode of action; it inhibits the reabsorption
> of sodium ions in exchange for potassium and hydrogen ions at that
> segment of the distal tubule under the control of adrenal
> mineralocorticoids (especially aldosterone). This activity is not
> directly related to aldosterone secretion or antagonism; it is a
> result of a direct effect on the renal tubule." (from:
> www.rxlist.com/cgi/generic/triamterine_cp.htm - Clinical Pharmacology
> tab).
>
> The same site can give information on Spironolactone for comparison
> (www.rxlist.com/cgi/generic/spiron_cp.htm).
>
>
>
>
> On Thu, 18 Jan 2007 00:29:58 GMT, "Mike" <mike@hotmail.com> wrote:

Thank you for the website...very informative.
>
> >Do you mean Triamterene does not block aldosterone, but works differently?
> >